Stroke triggers a hidden brain change that looks like rejuvenation

A team of physicists set out to test some of the most exciting claims in quantum computing—and found a very different story. Instead of confirming breakthroughs, their careful replication studies revealed that signals once hailed as major advances could actually be explained in simpler ways. Despite the importance of these findings, their work initially struggled to get published, highlighting a deeper issue in science.

A major new U.S. cholesterol guideline is shifting the focus toward earlier, more personalized prevention of heart disease. It urges people to start screening sooner—sometimes even in childhood—and highlights the importance of tracking not just LDL (“bad”) cholesterol but also genetic risk factors like lipoprotein(a). A new, more advanced risk calculator now uses broader health data to better predict heart attack and stroke risk over decades.

Nicotine e-cigarettes may be one of the most effective tools yet for quitting smoking, according to a sweeping review of global research. By analyzing findings from 14 major reviews spanning nearly a decade, researchers found consistent, high-quality evidence showing that nicotine vapes outperform traditional methods like patches, gum, and even behavioral support. While some lower-quality studies produced mixed results, the strongest data clearly favored nicotine e-cigarettes.

Scientists have developed a new gene therapy that quiets pain at its source in the brain—without the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted “off switch” that mimics morphine’s benefits but skips its dangerous side effects. In early tests, it delivered lasting relief without affecting normal sensations. The discovery could mark a major step toward safer, non-addictive pain treatments.