Nanobody repairs misfolded CFTR inside cells, boosting function in cystic fibrosis

The latest official stocktake of the state of New Zealand's freshwater carries many of the headline messages we have come to expect.

In the past several years, Rockefeller University's Kivanç Birsoy and his team in the Laboratory of Metabolic Regulation and Genetics have revealed remarkable details about the antioxidant glutathione, which plays many essential roles in the body, from clearing free radicals to repairing cellular damage. Among other things, they've discovered the transporter that shuttles glutathione to where it's needed, how glutathione keeps iron levels in check, and the metabolite's complicated relationship w

Bacterial sensors usually rely on emitting light to transfer information about what they're sensing, but that method isn't practical in many settings. That's why most information transmission is done via electricity. And while electricity-emitting bacteria exist, manipulating them into useful sensors has been quite challenging. Rice University professor Caroline Ajo-Franklin's group, working in collaboration with researchers from Tufts University and Baylor College of Medicine, recently develope

Restoring once abundant oyster reefs in temperate marginal seas such as the North Sea is a challenging task. New research by NIOZ marine ecologist Zhiyuan Zhao and colleagues shows that it is necessary to consider the short-term risk that introduced oysters will become buried by shifting sediment or will be dislodged by strong near-bed currents. For restoration success, these short-term physical disturbances can be more decisive than longer-term water-quality conditions. The results of pioneerin